Magnetic hyperthermia is one of the most promising technologies for cancer treatment. It consists of injecting nanoparticles into the tumor so that the generated heat burns it from the inside out. However, since the nanoparticle properties are highly dependent on particle and magnetic field properties, optimal dosage remains challenging. Researchers at the Adolphe Merkle Institute (AMI) of the University of Fribourg, along with colleagues from the Zurich University of Applied Sciences (ZHAW), have developed NanoLockin, a system which can optimize the production and dosing of those nanoparticles.

NanoLockin’s underlying measurement principle is based on lock-in thermography, a technology originally developed for the quality control of aircraft parts and widely used in engineering due to its exceptional sensitivity. By alternating magnetic field and infrared imaging, the heat produced by the nanoparticles can be precisely measured. The results are then evaluated using software specially developed for the system, explains a press release.

This project received the support of the Swiss Federal Commission for Technology and Innovation (CTI). Further applications of the NanoLockin technology are under development.